Markets

Protein hydrolysates

Protein Hydrolysates

Protein hydrolysates are a mixture of peptides and amino acids made by splitting a protein with acid, alkali or enzymes.

The protein hydrolysates from FrieslandCampina Domo are used in a wide number of high quality demanding markets around the globe.

  • Our Hyvital® products contribute to the success of many specialized infant nutrition formula and medical nutrition.
  • Proyield® and Stedygro® hydrolysates are key to the success of microbiological culture media and biopharmaceutical production

Discover comprehensive information on hydrolysates following our product website.


Hyvital®

We produce Hyvital® protein hydrolysates specifically designed for infant nutrition. We offer Hyvital ® protein hydrolysates to be used in hypoallergenic and specialized formulas. These hydrolysates are based on whey or casein.

For the hypoallergenic formulas we classify two focus areas:

  • CMA products, intended for formulas for infants suffering from cow’s milk allergy.
  • HA products intended for formulas to reduce the risk of the development of cow’s milk allergy.

Hyvital® Casein Phoshopeptides are offered for both infant and medical nutrition applications.

We offer Hyvital® Wheat Glutamine PN and Hyvital® Wheat Glutamine PN for medical applications.

Proyield® and Stedygro®

For biopharmaceutical cell culture media, Domo produces high-performance Proyield® protein hydrolysates based on non-animal protein. Domo knows best that reliable and consistent protein sources for promoting cell growth and production are vital to manufacturing biopharmaceuticals.

Characteristics of our Proyield® hydrolysates for BioPharma processes include:

  • Ultrafiltered, animal-free
  • Reduced endotoxins
  • No residual protease activity
  • Source of iron, trace minerals, amino acids and peptides

Our Stedygro® protein hydrolysates offer a highly processed and clarified product for all microbial culture media needs and assures accurate reactions and tests. Screening performed by FrieslandCampina Domo ensures a consistent performance time after time.

We offer a complete portfolio of hydrolysates for the cell nutrition market from different protein sources, including casein, whey, soy, wheat, cottonseed and pea.

< Back to Cell nutrition

Our protein hydrolysates ingredients


  • Hyvital® Casein CMA 500

    Hyvital® casein CMA 500 is an extensive hydrolyzed casein hydrolysate, with reduced allergenic properties. This product is intended for formulas for infants with existing cow’s milk allergy.

  • Hyvital® Casein HA 300

    Hyvital® casein HA 300 is a partially hydrolyzed casein hydrolysate, with reduced allergenic properties. This product is intended for formulas for infants with an increased risk to develop a cow’s milk protein allergy.

  • Hyvital® Whey CMA 500

    Hyvital® whey CMA 500 is an extensive hydrolyzed whey hydrolysate, with reduced allergenic properties.

  • Hyvital® Whey HA 300

    Hyvital® whey HA 300 is a partially hydrolyzed whey hydrolysate, with reduced allergenic properties. This product is intended for formulas for infants with an increased risk to develop a cow milk protein allergy.

  • Hyvital® Whey EtD 100

    Hyvital® Whey EtD 100 is a partially hydrolysed whey protein hydrolysate suitable for use in Easy-to-Digest concepts. It has a long history of safe use and is designed to meet the most stringent quality requirements operational in Europe.

  • Hyvital® Whey EtD 110

    Hyvital® Whey EtD 110 is a whey protein hydrolysate whereby specifically the ß-Lactoglobulin protein is broken down. The product has a long history of safe use and is designed to meet the most stringent quality requirements.

  • Proyield® Soy SE50MAF-UF

    Proyield® Soy SE50MAF-UF is an ultrafiltered animal free hydrolysate, based on soy protein, that contains a balance of protein and carbohydrates. This product is considered a standard that is used extensively in the BioPharma market.

  • Proyield® Soy SE70M-UF

    Proyield® Soy SE70M-UF is an ultrafiltered animal free protein hydrolysate, based on soy, that has a relatively higher protein content. When used in batch and feed media, this hydrolysate results in the production of high titers.

  • Proyield® Cotton CNE50M-UF

    Protein hydrolysate, based on cotton seed protein, that works effectively in various culture media.

  • Proyield® Pea PCE80B

    Ultra-filtered animal free protein hydrolysate, based on pea protein.

  • Proyield® Wheat WGE80M-UF

    This product is an ultrafiltered, animal free protein hydrolysate based on wheat protein, that supplies a stable form of glutamine to mammalian cells, thus supporting growth and titer in the cell culture process.

  • Stedygro® Casein CE90M

    Stedygro® hydrolysates represent top notch peptones for the cultivation of microbes on agar plates or in broths.

  • Stedygro® Casein CR90ML

    Acid digest of casein resulting in primarily free amino acids and short peptide fractions.

  • Stedygro® Casein CE90MPC

    Stedygro® Casein CE90MPC is produced by the controlled enzymatic digest of casein.

  • Stedygro® Casein CE90MX

    This peptone is manufactured by the controlled enzymatic digest of casein.

  • Proyield® Soy SE50MK-NK

    This product is an animal free protein hydrolysate containing a balance of protein and carbohydrates.

  • Stedygro® Soy SE50M

    Stedygro® Soy SE50M is produced by the controlled enzymatic digestion of soy flour. It is widely used in culture media for the cultivation of fastidious microorganisms.

  • Stedygro® Malt ME50MB

    Stedygro® Malt ME50MB peptone is a water soluble extract of malted barley. It is used in the isolation and cultivation of yeasts and molds from foods and for cultivating yeast and mold stocks.

  • Proyield® Whey LE80MX

    Enzymatically hydrolysed whey protein and casein, is used for partial replacement of fetal calf serum in tissue culture media.

  • Stedygro® Gelatin Yeast PP90M

    Enzymatically hydrolysed gelatin and yeast, is designed for media where maximum growth is desired. It may be used in place of meat peptones for culturing of fastidious microorganisms.

  • Stedygro® Gelatin GE90M

    Enzymatically hydrolysed gelatin, serves as a complex nitrogen source in bacteriological media

  • Proyield® Soy SE50MK

    Animal free protein and carbohydrate hydrolysate that supports a variety of culture types.
    This product is a mainstay in both mammalian cell culture, as well as, bacterial fermentation.

  • Proyield® Soy SE50MAF

    Proyield® Soy SE50MAF-UF is an ultrafilterd animal free hydrolysate, based on soy protein, that contains a balance of protein and carbohydrates. This product is considered a standard in the BioPharma market.

  • Hyvital® Rice CMA 500

    Hyvital ® Rice CMA 500 is a rice protein hydrolysate and is known to have reduced allergenic properties to be used in infant formulas1-2. Hyvital® Rice CMA 500 is manufactured under carefully controlled conditions using food-grade enzymes.

  • Hyvital® Wheat Glutamine PA

    Hyvital® Wheat Gluten PA is high in peptide-bonded Glutamine in acidic form.

  • Proyield® Cotton CNE50M

    Ultrafiltered, animal free protein hydrolysate, based on cotton seed protein, that works effectively in feed media. In batch media it can also promote significantly high titers.

  • Hyvital® Wheat Glutamine PN

    Hyvital® Wheat Glutamine PN is high in peptide-bonded Glutamine in neutral form. It is designed for use in medical nutrition products.